Multiple clinical studies have demonstrated the efficacy of NMES and sequential stimulation in the treatment of various musculoskeletal conditions. Below are links to some of these studies.
Electrical Muscle Stimulation as an Adjunct to Exercise Therapy in the Treatment of Nonacute Low Back Pain: A Randomized Trial
John A. Glaser, Matthew A. Baltz, Paul J. Nietert, and Christopher V. Bensen
Effect of sequential electrical surface stimulation on medication following Selective Endoscopic Discectomy™: Initial evaluation
Anthony T. Yeung, M.D., F.A.B.M.I.S.S., John Porter, M.D.
Electrical Stimulation Versus Voluntary Exercise in Strengthening Thigh Musculature After Anterior Cruciate Ligament Surgery
Anthony Delitto, Steven J. Rose, Joseph M. McKowen, Richard C. Lehman, James A. Thomas, Robert A. Shively
Electrical Changes in the Normal Quadriceps Femoris Muscle as a Result of Electrical Stimulation
R. Keith Laughman, James W. Youdas, Tom R. Garrett, Edmund Y. S. Chao
Improvement in Isometric Strength of the Quadriceps Femoris Muscle After Training with Electrical Stimulation
David M. Selkowitz
The Effects of Home Interferential Therapy on Post-Operative Pain, Edema, and Range of Motion of the Knee
Gregg J. Jarit, MD, Karen J. Mohr, PT, SCS, Robert Waller BS, and Ronald E. Glousman, MD
The Influence of Naloxone on Analgesia Produced by Peripheral Conditioning Stimulation
Bengt H. Sjölund, Margareta B. E. Eriksson
Ozcan J, Ward AR, Robertson VJ. A comparison of true and premodulated interferential currents. Arch Phys Med Rehabil 2004;85:409–15.